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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4526e40dd79701de8e9c13e1f8f7dfb482044365f97cd80d348b52a23f5a3ef1' 
  AND token = 'e/MvASRp4y0wIcDApidEdCH/PCZ23M4m2d2aIupDLbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}