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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fdd3cd48c52c55d7bb1cfc3d47fc611d2916c92091fd4e3973a9861cbbfe8bb' 
  AND token = '+W1+K5MGFC4QGEFfP55b6VfBUlUTBAzl/RmkjI0MP5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}