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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ad6f60ec1ef81a5ca5bec7381ddc3083bee053a1279d85eb89fe9131e01e771' 
  AND token = 'xox86BEDj1liZUNp4jcz0UqaxtUSJ04TMmk0y7sBHgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}