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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed250d863369425b831e46fe8b83e9a598ab711522a7ae78461b5afe85a47896' 
  AND token = 'i7Rs9UjbpF+rT8rBZugjz4i1lS9p+FDs5kGiQHv1u34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}