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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bcb634de36d64042302d6510c43a5badc26e320862a2c02f1ba91f27f7b81b5a' 
  AND token = 'mJhe+avi0dlZxFuz31xYGOa30lvaZsr1r/qmhb3E3co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}