SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1a14f3a7ba9855973aa239cc873985097ec528c6dde01ac6f003aced211e880' 
  AND token = 'Im+It3Vj4dUVmWNomH2AD0d0BjA3cb6yhlRIsRdcbh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}