SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f8f63be2fbfa93bcca46500d97c65a688e824f90a5c246b6c901bdff414493d' 
  AND token = 'ivDp+bqxadzFqRnRK3/xjhVf0Vdbo99Ozjt8wQawcRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}