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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f2f2e601f9aa8aa3baf394788b4d59688730c6897116795cd50aff94751089' 
  AND token = 'vpplV9B/6VTHEZczPZSkxM0pmCBCaYZ8d/RZ9Q5S0oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}