SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c545d6a872b9ea9117a5c5fb7c7cbcc360e0e569a8266b09048483db0a4e6b6d' 
  AND token = 'enxuT2eVLZrUp6TvCCnDk/zyVSYSCW3b2NapJugNqN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}