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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b65096a0df84b6931d1d4e9aac56466120b8c74108e30ec84910a62c79d11f0c' 
  AND token = 'jOZvjmBZPOi8+Lmjct98rnLEYBg8fDpGe5GHaxR0hl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}