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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81b62f82af7ebdd90b8ea5e349831e49a9c1c13a86b87fa4a5934ee4eb6d690' 
  AND token = 'HPdRQyqIlqoT+CFolD1fHgGCBzkKydmAPBttUb7B2R4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}