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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4e54d5f089ff7f1968b35342f8271c55890f6129954977768004f6752c15f4' 
  AND token = 'vljC8+Ss75Hx6d5psCNTYK5jBTwEyA/ylsEg0UjH1nA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}