SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4be28a7d9bde303e39c8dd475d8135352f7a78bb02610c701867549c6a6c4654' 
  AND token = 'Fjl2yxBFujW1QMrNuXNZKvtUDZIXO2a/3oziUyE8qb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}