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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe78e7e58d60a49a42b874c6db7e4e3918ff4ea6ff8950b0d54c816f1d293ad' 
  AND token = '0G6o/PQgLztDRMJ84F9BtTzz+p1s5m53vxMtUUWgxHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}