SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b39e0fae1264d0c7da7b281a0c932cb318fed9d5d1050b0dcac0fe1c3851000' 
  AND token = 'pHAAGdAOYlJQd4emrE1gh4WWzlJm9fypZngZvHfXijE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}