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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4515d9b526d42bae62ef4be117f9b7ab0b8a75ca7abb5287a61bb0e78f00d79' 
  AND token = 'KDUI1KHcIQyG8VoITkzZtZZ8rbAEc7aXxHe6v2d+wNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}