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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36501564c65ebeb5fa895e31b9986d4600b8c30a3728026e3c3ab2aa736b69d1' 
  AND token = 'vwxjf4rloId0JJLJWMuCfeZ+tCV0eTF4NnfVC8wnbrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}