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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18458dc1658b8c576f38770fcbe497d387502d4e7194b4c64ccd9582711f9f05' 
  AND token = '/fEIw9h5PSuz5pmaRmwJSfy9ZLuKzX9mJeFaEB0VhSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}