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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c52034207c4130c41a67cd3df1fb1e61cf6860ad4d7b0687375ae634c5533f' 
  AND token = 'vRO6saQaluN/q+ZNSzsMHvNJAbyaJ2E2eyfsdbZBNuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}