SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b562ad6b5af5285e3168926edee4856c8e187147fe6451e236ed94fb49640d9' 
  AND token = '1ISYO/9kgU4BZb0EirgXVOJL8m0VMy2sURY5tnkk/uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}