SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16933c7057c8062b303f15a9077e0667d4ad4768193910dff53e3459d7a686a0' 
  AND token = 'VRvtbNlkOrxLm3F4X9Dw2BeuG9LX+LrGJfjH4StO8AQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}