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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a0f18c5566708ecf2087cba24ba360ae6d9fdeb95e51c23dfc1e6a25e6aa6a0' 
  AND token = 'UGoQPFXQoJt0zHX+MYUvTj6mP2La5tzQ5oIo1wmrBWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}