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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5143aae3853a512f213bd95a3ca7cc2783e7c387ace975ddcb4efa0e6b110756' 
  AND token = 'Gxqfw9U/XobnnFsz7W4c2Dkc3ALQ9vXpRvCetuqqp1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}