SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0279b3b4fd3410111370d63d8799632b235cbb262237709b2e0a5dfd2e46e81d' 
  AND token = 'jKsIKejzdH3cOGIDord+Gl7ri3N6W5ZSh/oz6Rfxjm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}