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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a6d7ef83a2468b18d9ab5da89beca824d62d7ab29f3614a8394a511ce3f34bb' 
  AND token = '4x7lEMOtZ/82V5ns33dUHynFJA8sGfHzZAEiGvodHZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}