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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abfdd6dc3bf5bda4467c00194c6366e8c36a37e79082e4ee46bd4586cfd15833' 
  AND token = 'vrX58YgyDX+JUWUTLHnLlHdE0dm9C8Dmvsf02KYf4/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}