SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a44552dabc80f52c2e3183822384772a60f6dda39bf2335f14a3c7f32efb65b' 
  AND token = 'rE9gGY7uXM09xkFScIZ9DBcUDcAGxep/8eXkk2H/ytE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}