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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48cd0a240c3741b0b7d81b09a315933bb008021b402a9a4d14bcf2dc766fa9ec' 
  AND token = '1yHFky23uweiTt36FzcZcdfh+bxcpDkEibpTT4CNGpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}