SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46d1d4597c27c992fac9319aa3be75b87a0933d2376165a201c9dbf433fda007' 
  AND token = '/HkrLkLuNwcU/OfQTf379LYs4M1sINhKpGYIWJKqJV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}