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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d9d8ac962d826ba2d2327fdc5e5e1900d97888cd6301055b410d66cdd5bf309' 
  AND token = '6aB2lrCb9rftLBFFAxrMVW8acwsBH1VPaoMq0oewiVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}