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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb5b40a9f5d66ad7a414ba553ec8d9ea90997652886500980ebe6251113e1556' 
  AND token = 'Momulqygu1qeMR3b39xoSvbBSj2dm+rTeqkykl4GJhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}