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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60ad2fbc122a9fc654d2da5a6b73a9df1c6af94d63fe750132191e35c3aaff50' 
  AND token = 'YkVIo20Yq3bsogsGfMAO0JV7yvSlxLxfETnUQsc427k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}