SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '622a1671e9a553d9611885b9d975463a7988bb3194b56f7a1a2313aaa330b595' 
  AND token = 'o+RWsc+LpnXTgooC1vcJJgsU7D53B0rbr6pHK0WKKIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}