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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33be62f5a398a74f3665607646f4e912e8f2e0236144d0ebd2363f49a0176e3c' 
  AND token = 'Qu+0uM+DX3wtIYsixNfIJqgVm1ugU1Sj820v2OQ71gI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}