SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '059c4dca1e2984466c4af3f263ad48ed22477ec234bfc6fa69aaf1ee53066359' 
  AND token = 'uk1s7qYGIwPa4tW2XN2moOjJNEzHziYkRHmeJ2GQ/Nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}