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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4e3812f9de6c9f44c5e1e3db8eda727fde2ac1d8c1860af4788052ce8430b74' 
  AND token = 'y4RIQhuzcWXIzlthaEyGGrqeI0MXQs1ZxocDdrp4T4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}