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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4881a24855df4edf5a550178868f32dd11e73adb2d0e3545e7587c08a4814b24' 
  AND token = 'aj/GHbYr2XFApYsFzfF2IVl/wAMk8gnIrOKGtWTaDmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00119

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}