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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b3dba2d8476917d34cffb4c72d6a1c2f6af3c2b14d67090b4fd6bd49a0396bc' 
  AND token = 'VWuIoo912csA7rDLwAoN1taTW+nReFOvkLTCCKFoMMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}