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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4a289a8d58f096e59a77ad131a57a635a34130a0c86d6074e262397e60aecd5' 
  AND token = 'AwKz+Mnja37Ae6D3Q/CGaGPJjkW8z0uTkumsqDHxoaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}