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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '277c53175ad37d0786ae94120654e586caf18f7a10b2b0da5a644132c82a7ad5' 
  AND token = 'mvnAnPkDTJ19kY0yD+/jWNs0MR6/AY1g5PkbNtXcesA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}