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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26845d5d0814e5946e8317c2b96da7ec3ed81f071bdcc38788a82be5c883f290' 
  AND token = '9GH0v787z9OXW4j4KXL+eMFr5Xjjt2D3Uz7GiYqcIc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}