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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ee0f9c827589379c09c7b507d068cebc4a3eb705ce4982b1741ce4281887346' 
  AND token = 'pRvUVJwuQpJUOEkgIyE0RiGWIUy/6xGVbFFT7y5oCXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}