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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8edc17a2c6c4282ef7a6921b874ae7352549bdf5a2b4469d4c0838ef5041d725' 
  AND token = 'yvUqkd/d+NXTBw8ntl6WrqWcJfSP5xQQStcmBtk4GpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}