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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48278179c456a4160ba191409625c894a78be9d5374ae7dac8bb31a0f97d8689' 
  AND token = 'B6dt7+MkFIrMjH+CCtdfbWwVyRglcMj16aTUww0S0Pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}