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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b53b2ae99f79eac2c14d7ff7e8c72dbf56e92f8edbcba56bd9c423e516aed17' 
  AND token = '4q6jmE4aa1qu3SckV1SD01hVqJLWP20UD5U0BY+3/Ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}