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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c292b456eb676678a06e7c48313e4d542a664b8b501765482bab4b47869d748' 
  AND token = 'hbRkfOGJtBh1/ibwxuonsSsELIXZV4vENJi9ak0bPRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}