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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c551ae5d359ad3504a362350e88f9b1d1eb214d4c0774a750e4099f2f4cd12' 
  AND token = 'DLp4gxZ0tslKnx1Zc+pD45yy4ytIA1TayYiKp2raygg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}