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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c72b9a38a93c52e827b8c149ed6a3beafa449d2e0db929743eb2555ae6f6d73' 
  AND token = 'XKoXDOnaDtcCQia/0nqW+T8RsjgG06Qy4cnvc2dKFJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}