SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6f2d71e3d752e1d40e6b67a771097d1e362b1dc40b5230bf96e3745bf3c1179' 
  AND token = 'LTkwk1VwDmgl6pKFyNjU41E1CpBaPNghxteQdhCyDnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}