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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b87fdf16c78c2a560a87022e59401da587d31f609f74ebfa87ae413ffb3dee81' 
  AND token = 'sbGsNeL47Bq+DfO51EY9zNFHlktQo23nLL4/gEiUsoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}